Answer: With the projects with our colaborators in TUM hosipital, we used DiamondGAN for synthesizing missing modalities for MS and glioma patients. As mentioned in the miccai paper, the double inversion recovery (DIR) can be synthesized/well-reconstructed using FLAIR, T1 and T2.
Q. 2: Does DiamondGAN promise to genereate expected pathological information such as the texture of lesion or tumor?
Answer: you can combine as much information as possible from multiple sources. The hypothesis behind DiamondGAN is that the information of a target modality is distributed among other input modalities. Please see our experiment about the reconstruction of T1 constrast which requires a paramagnetic contrast agent. We somewhat failed to synthesize T1 contrast modality.