Using Copy Number data for significance while doing cohort analysis #938
satyakam001
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Hi, the more I keep using the tool, the more fascinating I find it to be.
While doing a cohort analysis using the CNV data, the results generated rank the genes' significance on the basis of their presence/absence. I was wondering if it is possible to determine the significance of the genes based on their status as gain of function/loss of function, or Amplification/Deletion/ShallowAmp/DeepDel?
We have a set of genes that are not significantly differentially mutated between different cohorts, but do show a major change in terms of gain/loss between the cohorts. It would be great if that data could be interpreted that way since it will have a significant biological implication. Is there an existing feature that can be used for this?
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