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I am trying to use FARFAR2 to model a sequence with triplexes in secondary structure. One of the types of triplexes is CGG triplex. Bond between C and the first G is the same as in the canonical base pair, so I can specify that in the dot-bracket notation, however, for the bond between two Gs, I think that I need to use the section 'Noncanonical pairs: Specify individual noncanonical pairs using both residues, the interacting edges (W/H/S for Watson-Crick, Hoogsteen, and sugar, or X for any), and finally the interaction orientation (either C/T for cis/trans or P/A for parallel/antiparallel, or X for any).'. However I do not understand how exactly what should I write here. Does anyone have a working example for any type of noncanonical structure?
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Hi,
I am trying to use FARFAR2 to model a sequence with triplexes in secondary structure. One of the types of triplexes is CGG triplex. Bond between C and the first G is the same as in the canonical base pair, so I can specify that in the dot-bracket notation, however, for the bond between two Gs, I think that I need to use the section 'Noncanonical pairs: Specify individual noncanonical pairs using both residues, the interacting edges (W/H/S for Watson-Crick, Hoogsteen, and sugar, or X for any), and finally the interaction orientation (either C/T for cis/trans or P/A for parallel/antiparallel, or X for any).'. However I do not understand how exactly what should I write here. Does anyone have a working example for any type of noncanonical structure?
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