diff --git a/.github/workflows/mypy-type-check.yml b/.github/workflows/mypy-type-check.yml
index 03f013862..2a86b874f 100644
--- a/.github/workflows/mypy-type-check.yml
+++ b/.github/workflows/mypy-type-check.yml
@@ -6,7 +6,7 @@ on:
   push:
     branches: [ develop, pre-release, master, main ]
   pull_request:
-    branches: [ develop, pre-release, master, main ]
+    branches: [ develop, pre-release, master, main, enhance-torch-compile ]
 
 jobs:
 
diff --git a/.github/workflows/python-package.yml b/.github/workflows/python-package.yml
index ed2d7a5fb..42919d024 100644
--- a/.github/workflows/python-package.yml
+++ b/.github/workflows/python-package.yml
@@ -8,7 +8,7 @@ on:
     branches: [ develop, pre-release, master, main ]
     tags: v*
   pull_request:
-    branches: [ develop, pre-release, master, main ]
+    branches: [ develop, pre-release, master, main, enhance-torch-compile ]
 
 jobs:
   build:
diff --git a/tests/conftest.py b/tests/conftest.py
index 682e893a8..98c35817c 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -587,11 +587,12 @@ def data_path(tmp_path_factory: pytest.TempPathFactory) -> dict[str, object]:
 # -------------------------------------------------------------------------------------
 
 
-def timed(fn: Callable) -> (Callable, float):
+def timed(fn: Callable, *args: object) -> (Callable, float):
     """A decorator that times the execution of a function.
 
     Args:
         fn (Callable): The function to be timed.
+        args (object): Arguments to be passed to the function.
 
     Returns:
         A tuple containing the result of the function
@@ -602,13 +603,13 @@ def timed(fn: Callable) -> (Callable, float):
         start = torch.cuda.Event(enable_timing=True)
         end = torch.cuda.Event(enable_timing=True)
         start.record()
-        result = fn()
+        result = fn(*args)
         end.record()
         torch.cuda.synchronize()
         compile_time = start.elapsed_time(end) / 1000
     else:
         start = time.time()
-        result = fn()
+        result = fn(*args)
         end = time.time()
         compile_time = end - start
     return result, compile_time
diff --git a/tests/models/test_patch_predictor.py b/tests/models/test_patch_predictor.py
index ab59efc53..e72096be7 100644
--- a/tests/models/test_patch_predictor.py
+++ b/tests/models/test_patch_predictor.py
@@ -13,7 +13,8 @@
 import torch
 from click.testing import CliRunner
 
-from tiatoolbox import cli
+from tests.conftest import timed
+from tiatoolbox import cli, logger, rcParam
 from tiatoolbox.models import IOPatchPredictorConfig, PatchPredictor
 from tiatoolbox.models.architecture.vanilla import CNNModel
 from tiatoolbox.models.dataset import (
@@ -1226,3 +1227,54 @@ def test_cli_model_multiple_file_mask(remote_sample: Callable, tmp_path: Path) -
     assert tmp_path.joinpath("2.merged.npy").exists()
     assert tmp_path.joinpath("2.raw.json").exists()
     assert tmp_path.joinpath("results.json").exists()
+
+
+# -------------------------------------------------------------------------------------
+# torch.compile
+# -------------------------------------------------------------------------------------
+
+
+def test_patch_predictor_torch_compile(
+    sample_patch1: Path,
+    sample_patch2: Path,
+    tmp_path: Path,
+) -> None:
+    """Test torch.compile functionality.
+
+    Args:
+        sample_patch1 (Path): Path to sample patch 1.
+        sample_patch2 (Path): Path to sample patch 2.
+        tmp_path (Path): Path to temporary directory.
+    """
+    torch_compile_enabled = rcParam["enable_torch_compile"]
+    torch._dynamo.reset()
+    rcParam["enable_torch_compile"] = True
+    # Test torch.compile with default mode
+    rcParam["torch_compile_mode"] = "default"
+    _, compile_time = timed(
+        test_patch_predictor_api,
+        sample_patch1,
+        sample_patch2,
+        tmp_path,
+    )
+    logger.info("torch.compile default mode: %s", compile_time)
+    torch._dynamo.reset()
+    rcParam["torch_compile_mode"] = "reduce-overhead"
+    _, compile_time = timed(
+        test_patch_predictor_api,
+        sample_patch1,
+        sample_patch2,
+        tmp_path,
+    )
+    logger.info("torch.compile reduce-overhead mode: %s", compile_time)
+    torch._dynamo.reset()
+    rcParam["torch_compile_mode"] = "max-autotune"
+    _, compile_time = timed(
+        test_patch_predictor_api,
+        sample_patch1,
+        sample_patch2,
+        tmp_path,
+    )
+    logger.info("torch.compile max-autotune mode: %s", compile_time)
+    torch._dynamo.reset()
+    rcParam["enable_torch_compile"] = torch_compile_enabled
diff --git a/tests/test_utils.py b/tests/test_utils.py
index faab9ac17..cf76028aa 100644
--- a/tests/test_utils.py
+++ b/tests/test_utils.py
@@ -13,6 +13,7 @@
 import numpy as np
 import pandas as pd
 import pytest
+import torch
 from PIL import Image
 from requests import HTTPError
 from shapely.geometry import Polygon
@@ -21,6 +22,7 @@
 from tiatoolbox import utils
 from tiatoolbox.annotation.storage import SQLiteStore
 from tiatoolbox.models.architecture import fetch_pretrained_weights
+from tiatoolbox.models.architecture.utils import compile_model
 from tiatoolbox.utils import misc
 from tiatoolbox.utils.exceptions import FileNotSupportedError
 from tiatoolbox.utils.transforms import locsize2bounds
@@ -1819,3 +1821,19 @@ def test_patch_pred_store_persist_ext(tmp_path: pytest.TempPathFactory) -> None:
     # check correct error is raised if coordinates are missing
     with pytest.raises(ValueError, match="coordinates"):
         misc.dict_to_store(patch_output, (1.0, 1.0))
+
+
+def test_torch_compile_already_compiled() -> None:
+    """Test that torch_compile does not recompile a model that is already compiled."""
+    # Create a simple model
+    model = torch.nn.Sequential(torch.nn.Linear(10, 10), torch.nn.Linear(10, 10))
+
+    # Compile the model
+    compiled_model = compile_model(model)
+
+    # Compile the model again
+    recompiled_model = compile_model(compiled_model)
+
+    # Check that the recompiled model
+    # is the same as the original compiled model
+    assert compiled_model == recompiled_model
diff --git a/tiatoolbox/models/architecture/__init__.py b/tiatoolbox/models/architecture/__init__.py
index 9ac1bbd82..6fac9b08b 100644
--- a/tiatoolbox/models/architecture/__init__.py
+++ b/tiatoolbox/models/architecture/__init__.py
@@ -150,6 +150,7 @@ def get_pretrained_model(
     model.load_state_dict(saved_state_dict, strict=True)
 
     # !
+
     io_info = info["ioconfig"]
     creator = locate(f"tiatoolbox.models.engine.{io_info['class']}")
 
diff --git a/tiatoolbox/models/architecture/utils.py b/tiatoolbox/models/architecture/utils.py
index cefeca1c3..94f970df8 100644
--- a/tiatoolbox/models/architecture/utils.py
+++ b/tiatoolbox/models/architecture/utils.py
@@ -2,10 +2,60 @@
 
 from __future__ import annotations
 
+import sys
+from typing import Callable
+
 import numpy as np
 import torch
 from torch import nn
 
+from tiatoolbox import logger
+
+
+def compile_model(
+    model: nn.Module | None = None,
+    *,
+    mode: str = "default",
+    disable: bool = False,
+) -> Callable:
+    """A decorator to compile a model using torch-compile.
+
+    Args:
+        model (torch.nn.Module):
+            Model to be compiled.
+        mode (str):
+            Mode to be used for torch-compile. Available modes are
+            `default`, `reduce-overhead`, `max-autotune`, and
+            `max-autotune-no-cudagraphs`.
+        disable (bool):
+            If True, torch-compile will be disabled.
+
+    Returns:
+        Callable:
+            Compiled model.
+
+    """
+    if disable:
+        return model
+
+    # This check will be removed when torch.compile is supported in Python 3.12+
+    if sys.version_info >= (3, 12):  # pragma: no cover
+        logger.warning(
+            ("torch-compile is currently not supported in Python 3.12+. ",),
+        )
+        return model
+
+    if isinstance(
+        model,
+        torch._dynamo.eval_frame.OptimizedModule,  # skipcq: PYL-W0212 # noqa: SLF001
+    ):
+        logger.warning(
+            ("The model is already compiled. ",),
+        )
+        return model
+
+    return torch.compile(model, mode=mode, disable=disable)
+
 
 def centre_crop(
     img: np.ndarray | torch.tensor,
diff --git a/tiatoolbox/models/engine/patch_predictor.py b/tiatoolbox/models/engine/patch_predictor.py
index 0bc570e69..2aede1393 100644
--- a/tiatoolbox/models/engine/patch_predictor.py
+++ b/tiatoolbox/models/engine/patch_predictor.py
@@ -11,8 +11,9 @@
 import torch
 import tqdm
 
-from tiatoolbox import logger
+from tiatoolbox import logger, rcParam
 from tiatoolbox.models.architecture import get_pretrained_model
+from tiatoolbox.models.architecture.utils import compile_model
 from tiatoolbox.models.dataset.classification import PatchDataset, WSIPatchDataset
 from tiatoolbox.models.engine.semantic_segmentor import IOSegmentorConfig
 from tiatoolbox.utils import misc, save_as_json
@@ -250,7 +251,13 @@ def __init__(
 
         self.ioconfig = ioconfig  # for storing original
         self._ioconfig = None  # for storing runtime
-        self.model = model
+        self.model = (
+            compile_model(  # for runtime, such as after wrapping with nn.DataParallel
+                model,
+                mode=rcParam["torch_compile_mode"],
+                disable=not rcParam["enable_torch_compile"],
+            )
+        )
         self.pretrained_model = pretrained_model
         self.batch_size = batch_size
         self.num_loader_worker = num_loader_workers