DESCRIPTION

Package: pksensi
Title: Global Sensitivity Analysis in Physiologically Based Kinetic Modeling
Version: 1.2.3
Authors@R: 
    c(person(given = "Nan-Hung", 
             family = "Hsieh", 
             role = c("aut", "cre"),
             email = "d99622005@ntu.edu.tw",
             comment = c(ORCID = "0000-0003-0163-2766")),
      person(given = "Brad", 
             family = "Reisfeld",
             role = "ctb", 
             comment = c(ORCID = "0000-0003-1310-1495")),
      person(given = "Weihsueh A.", 
             family =  "Chiu", 
             role = "ctb", 
             comment = c(ORCID = "0000-0002-7575-2368")))
Description: Applying the global sensitivity analysis workflow to investigate 
    the parameter uncertainty and sensitivity in physiologically based 
    kinetic (PK) models, especially the physiologically based 
    pharmacokinetic/toxicokinetic model with multivariate outputs. 
    The package also provides some functions to check the convergence 
    and sensitivity of model parameters. The workflow was first mentioned 
    in Hsieh et al., (2018) <doi:10.3389/fphar.2018.00588>, then further 
    refined (Hsieh et al., 2020 <doi:10.1016/j.softx.2020.100609>).                
License: GPL-3 | file LICENSE    
URL: https://github.com/nanhung/pksensi, 
    https://nanhung.github.io/pksensi/
BugReports: https://github.com/nanhung/pksensi/issues
Depends: 
    R (>= 4.1)
Imports:
    ggplot2,
    data.table,
    deSolve,
    foreach,
    parallel,
    doParallel
Suggests:
    covr,
    knitr,
    httk,
    rmarkdown,
    testthat
VignetteBuilder: 
    knitr
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.1
Language: en-US
Roxygen: list(markdown = TRUE)