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DESCRIPTION
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Package: quantiseqr
Title: Quantification of the Tumor Immune contexture from RNA-seq data
Version: 1.15.0
Authors@R:
c(
person(
given = "Federico", family = "Marini", role = c("aut", "cre"),
email = "[email protected]", comment = c(ORCID = "0000-0003-3252-7758")
),
person(
given = "Francesca", family = "Finotello", role = "aut",
email = "[email protected]", comment = c(ORCID = "0000-0003-0712-4658")
)
)
Description: This package provides a streamlined workflow for the quanTIseq method,
developed to perform the quantification of the Tumor Immune contexture from
RNA-seq data. The quantification is performed against the TIL10 signature
(dissecting the contributions of ten immune cell types), carefully crafted
from a collection of human RNA-seq samples. The TIL10 signature has been
extensively validated using simulated, flow cytometry, and
immunohistochemistry data.
License: GPL-3
Depends:
R (>= 4.1.0)
Imports:
Biobase,
limSolve,
MASS,
methods,
preprocessCore,
stats,
SummarizedExperiment,
ggplot2,
tidyr,
rlang,
utils
Suggests:
AnnotationDbi,
BiocStyle,
dplyr,
ExperimentHub,
GEOquery,
knitr,
macrophage,
org.Hs.eg.db,
reshape2,
rmarkdown,
testthat,
tibble
biocViews:
GeneExpression, Software, Transcription, Transcriptomics, Sequencing, Microarray,
Visualization, Annotation, ImmunoOncology, FeatureExtraction, Classification,
StatisticalMethod, ExperimentHubSoftware, FlowCytometry
VignetteBuilder: knitr
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2