From eff64f8db4da133f93940865615741bc02c661ba Mon Sep 17 00:00:00 2001 From: Alida Avola <81253886+AvolaAmg@users.noreply.github.com> Date: Mon, 28 Oct 2024 11:11:10 +0000 Subject: [PATCH] NTR Immature neurons and immature cortical neurons (#2635) Fixes #2436 --- src/ontology/cl-edit.owl | 22 ++++++++++++++++++++++ 1 file changed, 22 insertions(+) diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl index 9ab4c1034..e9e583c0c 100644 --- a/src/ontology/cl-edit.owl +++ b/src/ontology/cl-edit.owl @@ -3073,6 +3073,8 @@ Declaration(Class(obo:CL_4042024)) Declaration(Class(obo:CL_4042025)) Declaration(Class(obo:CL_4042026)) Declaration(Class(obo:CL_4042027)) +Declaration(Class(obo:CL_4042028)) +Declaration(Class(obo:CL_4042029)) Declaration(Class(obo:CL_4042031)) Declaration(Class(obo:CL_4042032)) Declaration(Class(obo:CL_4047006)) @@ -32548,6 +32550,26 @@ AnnotationAssertion(rdfs:label obo:CL_4042027 "GABAergic interneuron of the post SubClassOf(obo:CL_4042027 obo:CL_0002614) SubClassOf(obo:CL_4042027 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001903)) +# Class: obo:CL_4042028 (immature neuron) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31096632") Annotation(oboInOwl:hasDbXref "PMID:32116519") Annotation(oboInOwl:hasDbXref "PMID:37833544") obo:IAO_0000115 obo:CL_4042028 "A neuron in the central nervous system that is not committed to a differentiated fate, has not been newly derived from neurogenesis, and does not integrate into any circuit.") +AnnotationAssertion(terms:contributor obo:CL_4042028 ) +AnnotationAssertion(terms:date obo:CL_4042028 "2024-10-10T09:14:45Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32116519") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042028 "IN") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32116519") rdfs:comment obo:CL_4042028 "It is hypothesised that immature neurons can be utilised as a neurogenic reserve and that they can be involved in circuit plasticity.") +AnnotationAssertion(rdfs:label obo:CL_4042028 "immature neuron"@en) +SubClassOf(obo:CL_4042028 obo:CL_0000117) + +# Class: obo:CL_4042029 (cortical immature neuron) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37833544") obo:IAO_0000115 obo:CL_4042029 "An immature neuron of a cerebral cortex. This neuron develops prenatally and remains in an immature state throughout the lifespan of the organism.") +AnnotationAssertion(terms:contributor obo:CL_4042029 ) +AnnotationAssertion(terms:date obo:CL_4042029 "2024-10-10T09:14:54Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37833544") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042029 "cIN") +AnnotationAssertion(rdfs:label obo:CL_4042029 "cortical immature neuron"@en) +SubClassOf(obo:CL_4042029 obo:CL_4042028) +SubClassOf(obo:CL_4042029 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000956)) + # Class: obo:CL_4042031 (immune oligodendroglia) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30747918") Annotation(oboInOwl:hasDbXref "PMID:35301426") Annotation(oboInOwl:hasDbXref "PMID:35615276") Annotation(oboInOwl:hasDbXref "PMID:35662200") obo:IAO_0000115 obo:CL_4042031 "An oligodendrocyte of the central nervous system that exhibits immune properties such as self-presentation and non-self antigen presentation to T cells, phagocytosis of debris, and cytokine and chemokine production. Immune oligodendroglia is immunoreactive during inflammation, neurodegenerative disorders, chronic stress and major depressive disorder.")