DESCRIPTION

Package: mmsig
Title: A Mutational Signature Fitting Tool for Hematological Cancers
Version: 2.0
Authors@R: c(
    person(given = "Even", family = "Rustad", role = c("aut", "cre"), 
           email = "ehrustad@gmail.com",comment = c(ORCID = "https://orcid.org/0000-0002-9320-4963")),
    person(given = "Nicos", family = "Angelopoulos", role = "aut", email = "nicos.angelopoulos@gmail.com"),
    person(given = "Francesco", family = "Maura", role = c("aut", "cph"), email = "mauraf@mskcc.org")
           )
Description: A mutational signature fitting approach based on a expectation maximization algorithm 
            and using cosine similarities for dynamic error suppression. Provides bootstrapping-based 
            confidence intervals and assessment of transcriptional strand bias. 
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.1
biocViews:
Imports: 
    seqinr,
    plyr,
    tibble,
    tidyr,
    dplyr,
    ggplot2,
    reshape2,
    RColorBrewer,
    BSgenome,
    BSgenome.Hsapiens.UCSC.hg38,
    TxDb.Hsapiens.UCSC.hg19.knownGene,
    TxDb.Hsapiens.UCSC.hg38.knownGene,
    MutationalPatterns,
    deconstructSigs,
    GenomicFeatures,
    GenomicRanges,
    IRanges,
    GenomeInfoDb
Depends: 
    R (>= 2.10),
    BSgenome.Hsapiens.UCSC.hg19