diff --git a/app/controllers/file_uploads_controller.rb b/app/controllers/file_uploads_controller.rb
index 4207743a95..1b5c7d473a 100644
--- a/app/controllers/file_uploads_controller.rb
+++ b/app/controllers/file_uploads_controller.rb
@@ -169,7 +169,7 @@ def create_product_survey_from_url
       begin
         url = params[survey_param][:location]
         ext = UrlService.find_or_create_by(location: url)
-        esp = ExternalServicePasser.where(passer_id: @product.id, external_service_id: ext.id).first
+        esp = ExternalServicePasser.where(passer: @product, external_service_id: ext.id).first
 
         if esp
           @flash_notice = "That Online Order Form already exists"
diff --git a/app/controllers/services_controller.rb b/app/controllers/services_controller.rb
index 84f4288edc..6bf88bbb5c 100644
--- a/app/controllers/services_controller.rb
+++ b/app/controllers/services_controller.rb
@@ -1,4 +1,53 @@
 # frozen_string_literal: true
 
 class ServicesController < ProductsCommonController
+  after_action :update_sanger_external_service, only: [:create, :update]
+
+  private
+
+  def permitted_params
+    params = super
+
+    if current_facility.sanger_sequencing_enabled?
+      params += %i[sanger_sequencing_enabled]
+    end
+
+    params
+  end
+
+  def update_sanger_external_service
+    return unless @product.sanger_sequencing_enabled_previously_changed?
+
+    if @product.sanger_sequencing_enabled?
+      ensure_sanger_url_service
+      flash[:info] = t("controllers.services.sanger_sequencing_enabled")
+    else
+      flash[:info] = t("controllers.services.sanger_sequencing_disabled")
+    end
+  end
+
+  ##
+  # Ensures UrlService exists for the product
+  # pointing to Sanger Submission
+  def ensure_sanger_url_service
+    return unless defined? new_sanger_sequencing_submission_path
+
+    sanger_external_service =
+      @product
+      .external_services
+      .matching_location(new_sanger_sequencing_submission_path)
+      .first
+
+    if sanger_external_service.blank?
+      Service.transaction do
+        external_service = UrlService.find_or_create_by(
+          location: new_sanger_sequencing_submission_url
+        )
+        ExternalServicePasser.create!(
+          external_service:,
+          passer: @product,
+        )
+      end
+    end
+  end
 end
diff --git a/app/models/external_services/external_service.rb b/app/models/external_services/external_service.rb
index fd819c368c..f937ee9686 100644
--- a/app/models/external_services/external_service.rb
+++ b/app/models/external_services/external_service.rb
@@ -3,7 +3,9 @@
 #
 # Represents a 3rd party service in use by the system
 class ExternalService < ApplicationRecord
-
   validates_presence_of :location
 
+  def self.matching_location(value)
+    where("location like ?", "%#{value}%")
+  end
 end
diff --git a/app/views/services/_service_fields.html.haml b/app/views/services/_service_fields.html.haml
new file mode 100644
index 0000000000..30a32259c3
--- /dev/null
+++ b/app/views/services/_service_fields.html.haml
@@ -0,0 +1,6 @@
+- if current_facility.sanger_sequencing_enabled?
+  = f.input :sanger_sequencing_enabled,
+    as: :boolean,
+    label: false,
+    inline_label: Service.human_attribute_name(:sanger_sequencing_enabled),
+    hint: t("services.service_fields.sanger.instruct.sanger_sequencing_enabled")
diff --git a/app/views/services/_service_manage_fields.html.haml b/app/views/services/_service_manage_fields.html.haml
new file mode 100644
index 0000000000..c491c99d67
--- /dev/null
+++ b/app/views/services/_service_manage_fields.html.haml
@@ -0,0 +1,2 @@
+- if current_facility.sanger_sequencing_enabled?
+  = f.input :sanger_sequencing_enabled
diff --git a/config/locales/en.controllers.yml b/config/locales/en.controllers.yml
index 594ba438f0..6063f2035f 100644
--- a/config/locales/en.controllers.yml
+++ b/config/locales/en.controllers.yml
@@ -214,6 +214,10 @@ en:
         error: "Our apologies, but an error occurred while importing: %{error}"
         job_is_queued: "The bulk import is being processed. A report will be sent to %{email} when complete."
 
+    services:
+      sanger_sequencing_enabled: Sanger has been enabled, make sure the Order Form is inactive.
+      sanger_sequencing_disabled: Sanger has been disabled, make sure the Order Form is active.
+
     schedule_rules:
       create: Schedule Rule was successfully created.
       update: Schedule Rule was successfully updated.
diff --git a/config/locales/en.models.yml b/config/locales/en.models.yml
index 744af156ac..ffcfa36262 100644
--- a/config/locales/en.models.yml
+++ b/config/locales/en.models.yml
@@ -322,6 +322,8 @@ en:
         unit_cost: Unit Cost
         unit_adjustment: Unit Adjustment
         unit_net_cost: Unit Net Cost
+      service:
+        sanger_sequencing_enabled: Sanger Enabled
       stored_file:
         file_file_size: File
       user_role:
diff --git a/config/locales/en.yml b/config/locales/en.yml
index ee9f12a903..4f23706cf8 100644
--- a/config/locales/en.yml
+++ b/config/locales/en.yml
@@ -1258,6 +1258,11 @@ en:
         shared: Shared schedule
       hints:
         schedule: You may share a schedule with other products. Choose an exisiting schedule or use an unshared schedule.
+  services:
+    service_fields:
+      sanger:
+        instruct:
+          sanger_sequencing_enabled: Enable Sanger submissions for this service
 
   notifications:
     index:
diff --git a/db/migrate/20250110132703_add_product_sanger_sequencing_enabled.rb b/db/migrate/20250110132703_add_product_sanger_sequencing_enabled.rb
new file mode 100644
index 0000000000..76c1b2d58d
--- /dev/null
+++ b/db/migrate/20250110132703_add_product_sanger_sequencing_enabled.rb
@@ -0,0 +1,7 @@
+# frozen_string_literal: true
+
+class AddProductSangerSequencingEnabled < ActiveRecord::Migration[7.0]
+  def change
+    add_column :products, :sanger_sequencing_enabled, :boolean, null: false, default: false
+  end
+end
diff --git a/db/schema.rb b/db/schema.rb
index d361f726a8..5669d36e76 100644
--- a/db/schema.rb
+++ b/db/schema.rb
@@ -10,7 +10,7 @@
 #
 # It's strongly recommended that you check this file into your version control system.
 
-ActiveRecord::Schema[7.0].define(version: 2024_12_12_185208) do
+ActiveRecord::Schema[7.0].define(version: 2025_01_10_132703) do
   create_table "account_facility_joins", id: :integer, charset: "utf8mb3", force: :cascade do |t|
     t.integer "facility_id", null: false
     t.integer "account_id", null: false
@@ -664,6 +664,7 @@
     t.integer "min_reserve_days"
     t.integer "max_reserve_days"
     t.boolean "start_time_disabled", default: false, null: false
+    t.boolean "sanger_sequencing_enabled", default: false, null: false
     t.index ["dashboard_token"], name: "index_products_on_dashboard_token"
     t.index ["facility_account_id"], name: "fk_facility_accounts"
     t.index ["facility_id"], name: "fk_rails_0c9fa1afbe"
diff --git a/spec/controllers/services_controller_spec.rb b/spec/controllers/services_controller_spec.rb
index b07ee1e1b1..39078238ba 100644
--- a/spec/controllers/services_controller_spec.rb
+++ b/spec/controllers/services_controller_spec.rb
@@ -105,6 +105,33 @@
       is_expected.to set_flash
       assert_redirected_to manage_facility_service_url(@authable, assigns(:product))
     end
+
+    context "when sanger is enabled" do
+      before do
+        sign_in @admin
+        facility.update(sanger_sequencing_enabled: true)
+        @params[:service][:sanger_sequencing_enabled] = true
+      end
+
+      it "creates an external service" do
+        expect { do_request }.to change {
+          @service.reload.external_services.count
+        }.by(1)
+      end
+
+      it "does not create an external service if it already exists" do
+        ExternalServicePasser.create(
+          passer: @service,
+          external_service: UrlService.create(
+            location: new_sanger_sequencing_submission_path
+          )
+        )
+
+        expect { do_request }.to_not change {
+          @service.reload.external_services.count
+        }
+      end
+    end
   end
 
   context "destroy" do
diff --git a/spec/system/admin/creating_a_service_spec.rb b/spec/system/admin/creating_a_service_spec.rb
index b1d96ba908..34867cbba8 100644
--- a/spec/system/admin/creating_a_service_spec.rb
+++ b/spec/system/admin/creating_a_service_spec.rb
@@ -9,7 +9,7 @@
   let(:logged_in_user) { director }
   before { login_as logged_in_user }
 
-  it "can create and edit a service" do
+  it "can create a service" do
     visit facility_products_path(facility)
     click_link "Services (0)", exact: true
     click_link "Add Service"
@@ -20,13 +20,6 @@
 
     expect(current_path).to eq(manage_facility_service_path(facility, Service.last))
     expect(page).to have_content("My New Service")
-
-    click_link "Edit"
-    fill_in "service[description]", with: "Some description"
-    click_button "Save"
-
-    expect(current_path).to eq(manage_facility_service_path(facility, Service.last))
-    expect(page).to have_content("Some description")
   end
 
   it "can add order forms" do
@@ -62,4 +55,34 @@
   context "when billing mode is Skip Review" do
     include_examples "creates a product with billing mode", "service", "Skip Review"
   end
+
+  context "when sanger enable is checked" do
+    let(:service) { Service.last }
+
+    it "does not show the checkbox if facility is not sanger enabled" do
+      expect(facility.sanger_sequencing_enabled).to be false
+
+      visit new_facility_service_path(facility)
+
+      expect(page).to_not have_field("service[sanger_sequencing_enabled]")
+    end
+
+    it "can enable sanger on service if sanger is enabled for facility" do
+      facility.update(sanger_sequencing_enabled: true)
+
+      visit new_facility_service_path(facility)
+
+      fill_in "service[name]", with: "Sanger Sequencing"
+      fill_in "service[url_name]", with: "sanger-sequencing"
+
+      check "service[sanger_sequencing_enabled]"
+
+      click_button "Create"
+
+      expect(page).to have_content("Service was successfully created")
+      expect(page).to have_content("Sanger has been enabled")
+
+      expect(service.external_services.length).to eq(1)
+    end
+  end
 end
diff --git a/spec/system/admin/editing_a_service_spec.rb b/spec/system/admin/editing_a_service_spec.rb
new file mode 100644
index 0000000000..11e2d210e9
--- /dev/null
+++ b/spec/system/admin/editing_a_service_spec.rb
@@ -0,0 +1,60 @@
+# frozen_string_literal: true
+
+require "rails_helper"
+
+RSpec.describe "Editing a Service" do
+  let(:facility) { create :setup_facility }
+  let(:service) { create :service, facility: }
+  let(:admin) { create :user, :administrator }
+
+  before do
+    login_as admin
+  end
+
+  it "can edit a service" do
+    visit edit_facility_service_path(facility, service)
+
+    fill_in "service[description]", with: "Some description"
+    click_button "Save"
+
+    expect(current_path).to eq(manage_facility_service_path(facility, Service.last))
+    expect(page).to have_content("Some description")
+  end
+
+  describe "sanger enable change" do
+    it "does not show sanger enable if facility is not sanger enabled" do
+      facility.update(sanger_sequencing_enabled: false)
+
+      visit edit_facility_service_path(facility, service)
+
+      expect(page).to_not have_field("service[sanger_sequencing_enabled]")
+    end
+
+    context "when facility is sanger enabled" do
+      before do
+        facility.update(sanger_sequencing_enabled: true)
+      end
+
+      it "can enable sanger for the service" do
+        visit edit_facility_service_path(facility, service)
+
+        check "service[sanger_sequencing_enabled]"
+        click_button "Save"
+
+        expect(page).to have_content("Service was successfully updated")
+        expect(page).to have_content("Sanger has been enabled")
+      end
+
+      it "can disable sanger for the service" do
+        service.update(sanger_sequencing_enabled: true)
+        visit edit_facility_service_path(facility, service)
+
+        uncheck "service[sanger_sequencing_enabled]"
+        click_button "Save"
+
+        expect(page).to have_content("Service was successfully updated")
+        expect(page).to have_content("Sanger has been disabled")
+      end
+    end
+  end
+end