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Fixes #2627 Revise logical definition of 'inflammatory macrophage' (#…
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…2633)

* Fixes #2627 Revise logical definition of 'inflammatory macrophage'

Fixes #2627 Revise logical definition of 'inflammatory macrophage'

* Replace GO term
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aleixpuigb authored Oct 10, 2024
1 parent a77bb66 commit f7d5887
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Showing 4 changed files with 321 additions and 133 deletions.
26 changes: 13 additions & 13 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3093,9 +3093,9 @@ Declaration(Class(obo:CL_4052010))
Declaration(Class(obo:CL_4052011))
Declaration(Class(obo:CL_4052012))
Declaration(Class(obo:CL_4052013))
Declaration(Class(obo:CL_4052014))
Declaration(Class(obo:CL_4052018))
Declaration(Class(obo:CL_4052019))
Declaration(Class(obo:CL_4052014))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand Down Expand Up @@ -11264,7 +11264,7 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000863 "classically activat
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28923980") oboInOwl:hasRelatedSynonym obo:CL_0000863 "M1 macrophage")
AnnotationAssertion(rdfs:comment obo:CL_0000863 "Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response).")
AnnotationAssertion(rdfs:label obo:CL_0000863 "inflammatory macrophage")
EquivalentClasses(obo:CL_0000863 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032611) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032635) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032640) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042554) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0051767)))
EquivalentClasses(obo:CL_0000863 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032611) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032635) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032640) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042554) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045428)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000863 obo:CL_0000861)

# Class: obo:CL_0000864 (tissue-resident macrophage)
Expand Down Expand Up @@ -32759,6 +32759,17 @@ AnnotationAssertion(rdfs:label obo:CL_4052013 "externa theca cell")
EquivalentClasses(obo:CL_4052013 ObjectIntersectionOf(obo:CL_0000503 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000156)))
SubClassOf(obo:CL_4052013 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_4052010))

# Class: obo:CL_4052014 (pancreatic islet capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") Annotation(oboInOwl:hasDbXref "PMID:27124642") Annotation(oboInOwl:hasDbXref "PMID:28396983") Annotation(oboInOwl:hasDbXref "PMID:33200981") obo:IAO_0000115 obo:CL_4052014 "A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture.")
AnnotationAssertion(terms:contributor obo:CL_4052014 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052014 "2024-09-30T14:36:12Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") Annotation(oboInOwl:hasDbXref "PMID:28396983") oboInOwl:hasBroadSynonym obo:CL_4052014 "islet endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") oboInOwl:hasBroadSynonym obo:CL_4052014 "pancreatic islet endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_4052014 "pancreatic islet capillary endothelial cell")
EquivalentClasses(obo:CL_4052014 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006)))
SubClassOf(obo:CL_4052014 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_4052018 (fallopian tube epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "Wikipedia:Fallopian_tube") obo:IAO_0000115 obo:CL_4052018 "Any epithelial cell that is part of the fallopian tube.")
Expand All @@ -32779,17 +32790,6 @@ SubClassOf(obo:CL_4052019 obo:CL_0000066)
SubClassOf(obo:CL_4052019 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003889))
SubClassOf(obo:CL_4052019 ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005929))

# Class: obo:CL_4052014 (pancreatic islet capillary endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") Annotation(oboInOwl:hasDbXref "PMID:27124642") Annotation(oboInOwl:hasDbXref "PMID:28396983") Annotation(oboInOwl:hasDbXref "PMID:33200981") obo:IAO_0000115 obo:CL_4052014 "A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture.")
AnnotationAssertion(terms:contributor obo:CL_4052014 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052014 "2024-09-30T14:36:12Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") Annotation(oboInOwl:hasDbXref "PMID:28396983") oboInOwl:hasBroadSynonym obo:CL_4052014 "islet endothelial cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16607697") oboInOwl:hasBroadSynonym obo:CL_4052014 "pancreatic islet endothelial cell")
AnnotationAssertion(rdfs:label obo:CL_4052014 "pancreatic islet capillary endothelial cell")
EquivalentClasses(obo:CL_4052014 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006)))
SubClassOf(obo:CL_4052014 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
Expand Down
1 change: 1 addition & 0 deletions src/ontology/imports/go_terms.txt
Original file line number Diff line number Diff line change
Expand Up @@ -12,3 +12,4 @@ GO:0000279
GO:0036053
GO:0036376
GO:1990573
GO:0045428
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